Evidence-first health & ageing science Newsletter
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Live Well Editorial Team

The Live Well News editorial team reports on human-health, physiology and ageing research - what the evidence actually says, properly cited. This is science reporting, not medical advice.

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Explainer

HIIT cut fat and held muscle in older adults, but the edge was small

In a 6-month trial of more than 120 healthy older adults, high-intensity interval training reduced fat while holding onto muscle, unlike moderate exercise, which shaved a little. The authors say the differences between intensities were small.

Fact-check

Calcium and vitamin D supplements do little to prevent fractures or falls

A review of 69 randomized trials and more than 150,000 people found that for healthy older adults, calcium, vitamin D, or both together did little to prevent fractures or falls.

Explainer

In a small trial, low-dose creatine improved reaction time in menopausal women

Researchers ran one of the first randomized trials of creatine in women going through menopause. At a modest daily dose, the supplement edged out a placebo on reaction time, brain creatine and cholesterol, though the study was small and lasted only eight weeks.

Explainer

Semaglutide slowed measures of biological aging in a small trial

Researchers reanalyzed a 32-week trial of semaglutide in 84 adults and found the drug slowed several DNA-based clocks of biological aging. The aging analysis was exploratory, and the group studied was specific.

News

Higher blood vitamin C is linked to more gray matter in older adults

In 2,044 older adults in Japan, those with lower vitamin C in their blood tended to have less gray matter and weaker connections in a key brain network. It is a snapshot, so it cannot show that vitamin C protects the brain.

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