Topic

Heart & Metabolic

Cardiometabolic health: weight, weight-loss drugs, blood sugar and diabetes, cholesterol, blood pressure and heart health.

Hands holding a blister pack of white capsules, with a breakfast plate on the table behind.

Safiglipron, a GLP-1 pill with no fasting rules, matched or beat dapagliflozin on blood sugar

Oct 21, 2026

A blood glucose meter, a lancing pen and a test strip pot beside a green apple on a teal surface.

Prediabetes on 3 tests tracked with 15-fold diabetes risk in a 20-year study of 7,186 Koreans

Oct 20, 2026

A woman seen from behind at a kitchen table eats with chopsticks while on a video call on a laptop.

Women weighed six months into an online tirzepatide program had lost 15.5%; the study had no comparison group

Oct 20, 2026

A blood glucose meter on a wooden table with a test strip holding a drop of blood, a fingertip and a lancing pen beside it.

CGM lowered blood sugar in type 2 diabetes without insulin, 0.9 HbA1c points more than routine care

Oct 19, 2026

Three blister strips of pale pink tablets laid side by side on a soft pink background.

Menopause hormone therapy linked to 17% fewer type 2 diabetes cases across 14 studies

Oct 16, 2026

A stethoscope, blue ECG electrode pads and small pots of white tablets resting on an ECG printout.

7 to 9.5 fewer years of life linked to heart disease, fatty liver, diabetes and obesity together

Oct 16, 2026

A hand holds up a thin syringe with a fine needle against a plain bright blue background.

Petrelintide users lost about 8% to 10% of body weight in 28 weeks in a phase 2 trial funded by its maker

Oct 16, 2026

A hand holds a smartphone with a blank screen beside a glucose meter, a lancing device and a strip container on a wooden table.

Three years on a glucose sensor linked to lower blood sugar and less urine protein, not better kidney function

Oct 14, 2026

A blue ashtray filled with stubbed-out cigarette butts and ash, with one cigarette resting on the rim.

Quitting smoking tied to less nerve damage in diabetes after six years, less kidney and eye damage after eight

Oct 14, 2026

A laboratory worker in a white gown and blue gloves carries a red rack filled with blood sample tubes.

A third of insured adults with diabetic-range lab results had no recorded diagnosis or no treatment a year on

Oct 14, 2026

A pregnant woman sits on a gray sofa taking a tablet from a pill organizer, a glass of water in the other hand.

Metformin in pregnancy was not linked to developmental problems at school age in 177,409 Australian children

Oct 12, 2026

A blood glucose meter, two syringes, a test strip and a blue ribbon laid out on a pale blue surface.

Survodutide cut body weight by 8% to 10% in people with type 2 diabetes, and most had gut side effects

Oct 12, 2026

Hands in blue gloves draw blood with a syringe from the inside of an arm that has a teal tourniquet above the elbow.

No blood test differed after fasts past 12 hours, and only a few after short fasts, in 101,148 patients

Oct 9, 2026

A teenager in a green sweatshirt sits with hands clasped while a clinician in teal scrubs, gloves and a face mask talks and gestures.

Obesity drugs for children: what a new WHO guideline says and what trials in under-12s and teenagers show

Oct 9, 2026

A glass of water with a few orange tablets beside it on a pink surface.

Orforglipron pill was no worse for the heart than insulin in a 2,749-person diabetes safety trial

Oct 9, 2026

A person in a sports top and dark leggings stands against a brick wall holding a tape measure out from the waist, face out of frame.

Top-dose retatrutide cut body weight 25% over 80 weeks in a 2,339-person trial, with gut side effects common

Oct 9, 2026

A blood glucose meter, a lancing pen and a test strip container laid in a row between two green apples on a teal background.

A low-calorie diet and supervised exercise put type 2 diabetes into remission in 27 of 50 adults aged 18 to 45

Oct 6, 2026

A person in a yellow sweater holding a pink measuring tape around the waist of someone in a pale green dress.

BMI: what body mass index measures, what it predicts about health and what it misses

Oct 4, 2026

A microscope lens positioned over a glass slide on the stage.

HPV infection linked to 7% higher cardiovascular disease risk in a study of 3 million Swedish women

Oct 4, 2026

A person with long hair typing on a keyboard at a desk in a dark room, face out of frame.

Long working hours and stroke: working 55 hours a week was tied to a one-third higher risk

Oct 4, 2026

A pregnant woman in a cream sweater seated at a white desk with both hands resting on the belly, face not shown.

Maternal obesity in pregnancy tied to higher offspring death rates into adulthood in 2.6 million births

Oct 4, 2026

A group of people seated around a wooden table sharing plates of pasta, salad and bread, seen from above.

Metabolism and age: energy use holds steady from 20 to 60 and then declines, in a study of 6,421 people

Oct 4, 2026

Two people holding hands across a table set with bread rolls on a plate and a cup of coffee.

Eating beside a partner blunted the blood sugar rise after a meal in 108 healthy young adults

Oct 2, 2026

An empty white plate with a single fork on it.

Does intermittent fasting help you lose weight? What the trials show

Sep 29, 2026

A smiling boy and an adult sharing a meal at an outdoor table with fruit and juice.

GLP-1 drugs in teens: 1 in 6 had a nutrient deficiency diagnosed within a year

Sep 26, 2026

A person measuring their waist with a tape measure.

Belly fat and low vitamin D together tied to more than double the risk of death after 50

Sep 26, 2026

Older hands holding an inhaler and a spacer outdoors

GLP-1 drugs went with 12% fewer asthma attacks than a rival diabetes drug, in 100,746 patients

Sep 23, 2026

The control panel and screen of an ultrasound machine in a clinic

Tirzepatide and semaglutide showed the same serious liver outcomes over about 17 months

Sep 23, 2026

A doctor listening to a child's chest with a stethoscope at a desk

GLP-1 prescriptions for children aged 8 to 11 rose 310-fold since 2019, in records of 3.5 million kids

Sep 23, 2026

A blood glucose meter, two syringes, tablets and a lancet pen laid out on a purple background

Heart benefit of GLP-1 drugs faded after people stopped, in 333,687 US veterans with type 2 diabetes

Sep 23, 2026

A laboratory microscope on a bench

Gut lining cells kept dying abnormally in bowel disease remission, and that signal predicted relapse

Sep 23, 2026

A meal seen from above: a salad with tomatoes, eggs and almonds, bread, strawberries and a glass of water

Eating healthily after a type 2 diabetes diagnosis went with longer survival, in 7,795 US adults over 24 years

Sep 22, 2026

A teaspoon resting in a spread of white sweetener crystals

Blood erythritol falling during weight loss went with slightly better heart risk scores, in 664 adults

Sep 22, 2026

A doctor holding a tablet talks with a young woman in a clinic consultation room

IUD placement hurt less with a numbing solution in the uterus, in a 370-person trial

Sep 22, 2026

A doctor in a white coat and mask talks with a woman sitting on a hospital bed

Liposuction eased leg pain in lipedema far more than compression, in a 410-woman trial

Sep 22, 2026

A person holding a small round wearable device against their abdomen

Insulin needs rose in the second half of the menstrual cycle, in 380 cycles from people with type 1 diabetes

Sep 22, 2026

Gloved hands holding a petri dish up to the light

Dietary cholesterol sent the liver's LDL receptors to be destroyed, in cells and mice

Sep 21, 2026

A gloved hand holding three blister strips of plain white tablets

Febuxostat matched allopurinol on heart events but went with more deaths in 7,555 matched pairs

Sep 21, 2026

A young woman sitting on the edge of a bed with her hands clasped, looking down

Young women with polycystic ovary syndrome had twice the odds of a psychiatric diagnosis

Sep 21, 2026

An older person holding up a single tablet, blister packs on the table in front of them

Thyroid tablets moved almost nothing in older adults with a borderline result, across 286 people

Sep 21, 2026

A hand holding a lancing device above an open palm

Glucose monitor patterns tracked with heart risk in 1,356 people who did not have diabetes

Sep 18, 2026

A gray and white rat standing up and sniffing the air against a black background

Gut bacteria may raise blood pressure by dampening a serotonin signal to the vagus nerve, rat study finds

Sep 17, 2026

A small brown mouse eating a nut on paving stones

Switching off a gut immune sensor protected male mice from diet-driven obesity through their gut bacteria

Sep 17, 2026

Two mice peering out from inside a glass jar

Fat cells in lean breast tissue release a molecule that kills cancer cells, and obesity reduces it

Sep 17, 2026

A gray rat eating a piece of food between two white and patched rats

Combining two next-generation weight-loss drugs beat either one alone in obese rats

Sep 17, 2026

A gloved hand loading a pipette into a laboratory sample plate

Carrying one copy of the alpha-1 antitrypsin variant raised liver risk, not just two

Sep 16, 2026

An empty operating theatre with surgical lights and equipment

Ultrasound-guided stenting cut cardiac deaths in East Asian trials and not in anyone else's

Sep 16, 2026

An ultrasound console screen beside two probes in their holders

How well the heart's upper chamber squeezed predicted deaths in amyloidosis; its size did not

Sep 16, 2026

Three hand-rolled joints on a scratched wooden table beside an ashtray

Regular cannabis users had 9% fewer extra heartbeats on days they were randomly assigned to inhale

Sep 14, 2026

A woman in her fifties holding a glass of water beside a window, a large green leaf in the foreground

Hormone therapy for hot flashes tied to lower heart risk when started within 10 years of menopause

Sep 14, 2026

Plain white tablets scattered across a yellow surface

Benefits of a type 1 diabetes pill faded within a year of patients stopping it

Sep 8, 2026

A bedside monitor showing vital signs next to a patient lying out of focus in a hospital bed

Turning on glucose monitor alarms helped hospital patients; making them predictive added nothing

Sep 8, 2026

A person pressing a fist against the center of their chest

One in three patients with chest pain and clear arteries had a hidden circulation problem

Sep 8, 2026

A pulse oximeter clipped onto a fingertip showing a reading

Pacemakers outperformed catheter ablation for irregular heart rhythm in patients over 75

Sep 8, 2026

A paper electrocardiogram printout showing heart rhythm traces

A newer heart rhythm ablation method carried a higher 30-day stroke risk than the older one

Sep 8, 2026

A moulded walking boot resting beside a pair of crutches

Hip fractures were five times more common in type 1 diabetes, peaking in people in their forties

Sep 8, 2026

A blood pressure cuff fastened around the arm of a patient lying in a hospital bed

A newer drug slowed kidney decline in people whose damage came from blood pressure, not diabetes

Sep 7, 2026

The control panel of an ultrasound machine, with trackball and dials

Liver stiffness readings used to judge fatty liver treatment were checked against biopsy for the first time

Sep 7, 2026

Electrocardiogram electrodes and a recorder resting on a printed heart trace

After a heart valve replacement, a blood thinner beat aspirin by nearly half

Sep 7, 2026

A person walking along a pavement, seen from behind at knee height

A statin alternative cut serious leg artery events by 36% in people who cannot take statins

Sep 6, 2026

A ring-shaped treatment scanner with an empty patient table

Left-side breast radiotherapy raised heart risk only in women who already had three risk factors

Sep 6, 2026

A gloved clinician taking blood from a person's inner wrist

A cholesterol drug cut deaths from any cause by 20% in people who had never had a heart attack

Sep 6, 2026

Hands using a glucose meter surrounded by test strips

Children exposed to diabetes in the womb developed it five times as often

Sep 6, 2026

A clinician holding an ultrasound probe in a scanning room

Losing a tenth of body weight tracked seven times the odds of cirrhosis recovering

Sep 6, 2026

A woman holding her eyelids open to put in eye drops

Eye drops improved vision in diabetic macular swelling, a condition normally treated by injection

Sep 4, 2026

A city skyline and hilltop observatory almost lost in thick gray haze

Heat and wildfire smoke together tracked more heart deaths than either alone

Sep 4, 2026

A clinician taking a blood pressure reading from a cuff on a patient's upper arm

Each 20-point drop in blood pressure tracked 24% fewer kidney failure deaths

Sep 2, 2026

A clinician in a white coat fitting trial lenses to an adult man's eye in a clinic

Fenofibrate tracked 68% less diabetic macular edema across 4,571 matched patients

Sep 2, 2026

A shared table spread with small dishes as several people serve themselves

Mediterranean living tracked half the heart deaths in adults with type 2 diabetes

Sep 2, 2026

Gloved hands giving an injection into a person's upper arm

Flu vaccination tracked 20% less new atrial fibrillation across 276,888 matched adults

Sep 1, 2026

An older couple walking arm in arm along a city street

Semaglutide and tirzepatide tracked half the femoral fractures of another diabetes drug

Sep 1, 2026

The lit display of a digital bathroom scale glowing in a dark room

Sitting at the top of the 'normal' BMI range carried 78% more type 2 diabetes across 1.8 million people

Aug 31, 2026

Electrode leads and clips laid across a printed heart rhythm trace

Pushing potassium to the top of the normal range cut atrial fibrillation events by a third in a trial

Aug 31, 2026

A stethoscope, a tape measure and small glass vials laid on a white surface

A third of people with 'preclinical' obesity crossed into the clinical kind within five years

Aug 31, 2026

Hands typing a message on a phone showing a thread of chat bubbles

Digital nudges lifted statin refills from 12% to 14%, and a second nudge worked as well as the first

Aug 31, 2026

A clinician listening to an older man's chest with a stethoscope

A raised heart-strain marker that came back down carried no extra risk eight years later

Aug 30, 2026

A clinician pointing at brain scans displayed on a lightbox

Stroke patients who hit the cholesterol target but had not halved it still had 12% more repeat events

Aug 30, 2026

A radiographer positioning a patient at the mouth of an MRI scanner

Lean people with fatty liver and no risk factors still faced 2.5 times the liver death rate

Aug 30, 2026

An aged hand tipping white tablets from an amber bottle into an open palm

A diabetes drug tracked a third fewer deaths in over-75s, alongside a stroke signal nobody can explain

Aug 30, 2026

Gloved hands pressing a dressing onto a bare upper arm after an injection

People given the newer shingles vaccine had 9% less heart disease over the next seven years

Aug 30, 2026

A close-up of an eye lit by a narrow band of light, iris and lashes in sharp detail

Sudden vision loss hit 3 more GLP-1 users per 10,000 over 18 months than two rival diabetes drugs

Aug 28, 2026

A dentist in blue gloves examining a patient's open mouth with a mirror and probe

Gum disease tracked 18 to 25% more new diabetes across 28 studies and 300,000 people

Aug 28, 2026

A gloved hand holding a dental instrument, with a reclining patient blurred behind

Treating gum disease lowered blood pressure by 4.64 mmHg across 12 randomized trials

Aug 28, 2026

A hand squeezing two blue rubber grip balls against a white background

Squeezing a handgrip for 12 weeks lowered blood pressure in medicated hypertensive women

Aug 26, 2026

A bowl of yogurt topped with strawberries and blueberries on a wooden table

Probiotics trimmed waist size in adults with metabolic syndrome, but left blood pressure alone

Aug 26, 2026

A low shot from behind of a walker's legs and white trainers mid-stride on a tree-lined tarmac park path

Brisk walking lowered blood pressure, but the benefit peaked near 460 MET-minutes a week

Aug 25, 2026

A person curled on their side on a sofa with both hands pressed to their abdomen

Endometriosis tracked more blood clots, from a low base

Aug 17, 2026

A person using a blue floss pick between their front teeth in a bathroom

Flossing tracked 23% fewer strokes in 98,866 Korean adults followed for nine years

Aug 17, 2026

An overhead view of people crossing a city street at a marked crosswalk

Walkable streets tracked lower diabetes risk, but clearly only in richer areas

Aug 17, 2026

A pair of feet in dark socks standing on a digital bathroom scale on a wooden floor

Weight lost early in prediabetes still counted 34 years on

Aug 14, 2026

White tablets and an open bottle on a yellow background

Melatonin worsened blood sugar, but only in gene carriers

Aug 6, 2026

Two small white tablets on a plain pink background

An oral GLP-1 pill cut weight 9% in a phase 2 trial

Aug 4, 2026

Two parents and two children preparing vegetables together at a kitchen counter

Adding family coaching to GP care worked for child obesity

Aug 3, 2026

A glowing blue heart rate trace running across a grid

Heart deaths halved since 1990. The causes swapped places.

Aug 3, 2026

A woman running a hand through her hair and looking toward the camera

GLP-1 drugs carried higher hair loss risk than two rivals

Aug 2, 2026

An older couple walking together through a meadow of wildflowers

Lifestyle cut chronic disease. Metformin did not.

Aug 2, 2026

Broken sheets of ice floating at the edge of dark cold water

Mild cold lowered blood sugar. Colder did nothing.

Aug 1, 2026

A person sitting alone on a chair beside a curtained window in a dim room

Loneliness tracked heart and metabolic disease across 33 countries

Aug 1, 2026

Two clinicians examining spine X-rays displayed on a lightbox

GLP-1 drugs tracked with fewer fractures, but only with diabetes

Jul 29, 2026

A patient in a hospital gown standing at a clinic weighing scale

Mazdutide took off 16.7% of body weight in a phase 3 trial

Jul 29, 2026

A person standing on a bathroom scale, seen from behind

The weight came back. The visceral fat loss didn't.

Jul 29, 2026

A gloved clinician giving an injection into an upper arm

COVID vaccine tied to fewer heart events in over-75s

Jul 28, 2026

Two teenagers playing on an outdoor running track

Weight-loss drugs worked better with lifestyle, not without

Jul 28, 2026

A person sitting on the edge of a bed with hands on their knees

Stopping GLP-1 drugs tracked with more anxiety after

Jul 28, 2026

Overlapping blister packs holding many different coloured tablets and capsules

Semaglutide led the field for antipsychotic weight gain

Jul 27, 2026

Masked surgeons working under theatre lights during an operation

Bariatric surgery cost less downstream than GLP-1 drugs

Jul 27, 2026

An empty residential street lined with terraced houses under a grey sky

Black women developed high blood pressure 9.6 years earlier

Jul 27, 2026

A hand operating the control panel of an ultrasound scanner

Survodutide cleared liver fat in 84% of patients

Jul 27, 2026

A close-up of a blood glucose meter beside a fingertip blood sample

Losing 15% early after a diabetes diagnosis cut complications

Jul 26, 2026

A healthcare worker measuring her blood pressure with an arm cuff

Obesity's metabolic risk gap has narrowed in older adults

Jul 26, 2026

A single white oval tablet on a pale blue background

Oral GLP-1 pill elecoglipron hit 10% weight loss in a trial

Jul 26, 2026

A man measuring his waist with a tape measure

Sarcopenic obesity tripled type 2 diabetes risk

Jul 26, 2026

A young girl smiling at a table behind a glass of juice, with whole oranges in the foreground

Childhood fruit juice tracks with high blood pressure at 36

Jul 25, 2026

A person holding a blue medical injection pen indoors

Apitegromab kept muscle on during tirzepatide weight loss

Jul 25, 2026

A person holding a cardboard box filled with fresh vegetables

Food-as-medicine groceries improved blood sugar in diabetes

Jul 25, 2026

An older woman standing alone at a window, holding the sheer curtain and gazing out

Loneliness was tied to a higher risk of heart valve disease

Jul 23, 2026

Plastic waste and debris strewn along a polluted riverbank

Heart attack patients carried more microplastics in blood

Jul 23, 2026

A fork wound with a blue measuring tape, held in one hand

Yo-yo dieting was tied to muscle loss on body scans

Jul 23, 2026

Blood sample vials in a laboratory rack

Why apoB may be a better cholesterol test than LDL

Jul 22, 2026

A close-up of ridged potato chips inside an open snack bag

Ultra-processed food tied to 19% higher heart-death risk

Jul 21, 2026