Evidence-first health & aging science Newsletter
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Topic

Supplements

Pills, powders and compounds: vitamins and minerals, performance and longevity supplements, herbals, and safety.

A tipped-over glass jar spilling yellow softgel capsules onto a white surface.
News

Unplanned analysis ties higher DHA dose to fewer early preterm births in women with a gene variant

Oct 20, 2026

Overhead view of an open jar of peanut paste resting on a bed of shelled peanuts.
News

Free nutrient sachets lifted measles vaccination by 20 points in a Nigerian trial

Oct 19, 2026

A backpacker seen from behind walks up a gravel track through a mountain valley with snowy peaks under blue sky.
News

Travelan colostrum showed no clear protection from travelers' diarrhea in an 850-person trial

Oct 16, 2026

Three clear yellow softgel capsules lie on a dark reflective surface beside a white bottle and its cap.
News

High-dose vitamin D in pregnancy did not leave children with stronger bones at 13, a Danish trial found

Oct 14, 2026

A person in a black shirt holds a shaker bottle with a red lid at the hip, the other hand resting on the waist, outdoors.
Explainer

Protein powder: what it adds to weight training, where the benefit levels off and what it does not do

Oct 14, 2026

Clear capsules filled with speckled brown powder lie scattered on a bright yellow surface.
Explainer

Tainted supplements: which products the FDA has found to contain hidden drugs, and what was in them

Oct 14, 2026

A hand tips white capsules from an unlabelled amber bottle into an open palm against a pink background.
News

Nicotinamide riboside, an NAD supplement, did not slow early Parkinson's and did slightly worse than placebo

Oct 12, 2026

Clear yellow softgel capsules, small corked glass bottles of powder and yellow flowers scattered on a yellow surface.
News

Urolithin A did not improve blood vessel function in a four-week trial of 50 adults with obesity

Oct 12, 2026

A beige capsule beside a small heap of beige powder, and a green and white capsule beside a heap of brown powder, on a green surface.
Explainer

Kratom explained: what the leaf is, how lab-made versions differ and what the evidence shows on risk

Oct 9, 2026

Capsules spilling from a small white bowl beside halved lemons and pieces of ginger on a round cork mat.
News

Vitamin C did not slow abnormal blood cell growth in a 109-person trial; an unplanned tally found fewer deaths

Oct 9, 2026

Amber softgel capsules and pale round tablets scattered across a marble surface, with a tin of white capsules at the edge.
Explainer

Vitamin D2 or D3: what the evidence shows after a review found D2 supplements lower the body's D3

Oct 9, 2026

An open palm holding two green-beige capsules while the other hand picks up a third.
Explainer

Glucosamine and Alzheimer's: what a study tying the joint supplement to faster decline does and does not show

Oct 6, 2026

Three spoons of powder, brown, green and white, on a white surface.
Explainer

Do collagen supplements work? What trials show for skin and joints

Sep 29, 2026

A hand dropping a white tablet into a glass of water against a lavender background.
Explainer

Does magnesium help you sleep? What the trials show

Sep 29, 2026

Assorted white tablets, capsules and a red softgel on a yellow background.
Explainer

Do multivitamins help people live longer? What the research shows

Sep 29, 2026

White capsules and golden softgels scattered on a marble surface.
Explainer

Does vitamin D help after a heart attack? What the TARGET-D trial found

Sep 29, 2026

Three white tablets and a yellow capsule in a row on a green background.
News

Vitamin K2 and D3 supplements slowed coronary calcium buildup in a 398-person trial

Sep 29, 2026

A clear, unlabeled bottle filled with golden softgel capsules.
Explainer

Can pentadecanoic acid reverse aging? What the evidence shows

Sep 28, 2026

A person lying in bed with a cold, blowing their nose into a tissue.
Explainer

Can vitamin C cure a cold? What the trials show

Sep 28, 2026

Two dental professionals treating a patient reclined in a dental chair.
Explainer

Omega-3 plus low-dose aspirin matched antibiotics as an add-on for severe gum disease in a small trial

Sep 26, 2026

A pregnant person and a partner sitting together at a kitchen table with mugs and a phone
News

Higher vitamin B12 in both parents before conception went with fewer birth defects, in a Chinese study

Sep 22, 2026

A white bowl of eggs nestled in straw on a wooden board
News

Chicken and eggs enriched with vitamin D held off the winter dip in 57 young adults, but a pill did more

Sep 22, 2026

Golden softgel capsules in a small white bowl on marble, a few scattered beside it
Explainer

Vitamin D halved the return of positional vertigo over two years in 160 deficient patients

Sep 21, 2026

An older woman raising a pair of small dumbbells beside a tall window
News

Creatine held on to lean tissue during a 12-week weight-loss program in 64 middle-aged adults

Sep 20, 2026

A kale salad topped with walnuts and pomegranate seeds
News

A compound gut bacteria make from pomegranates and walnuts strengthened the gut lining in mice

Sep 18, 2026

Small clear yellow softgel capsules scattered across a white marble surface
News

Vitamin D at 1,600 or 3,200 IU a day did not cut fractures in older adults, most of whom were not deficient

Sep 14, 2026

Mixed nuts including brazil nuts scattered on dark wood
News

A selenium supplement lowered long-term blood sugar by 1.2 points in eight weeks

Sep 6, 2026

A spread of dark leafy greens including kale and cabbage on a dark surface
News

Vitamin K from leafy greens tracked 14% less dementia over 28 years; the other form went the wrong way

Sep 1, 2026

Assorted supplement capsules in small bowls on a pale surface
News

Zinc cut infections by 38% in young children with sickle cell disease in a Ugandan trial

Sep 1, 2026

Garlic bulbs and loose pink-skinned cloves spilling from a hessian sack onto a wooden surface
News

Garlic lowered average blood sugar by half a point across 27 trials, but fasting glucose barely moved

Aug 25, 2026

A close-up of a three-lobed strawberry leaf against blurred brown undergrowth
News

Strawberry leaf extract failed its pre-planned memory test, then reported a win anyway

Aug 24, 2026

A glass jar of yellow softgel capsules with several spilled onto a pale surface
News

Vitamin D missed its target in depressed young people

Aug 16, 2026

A glass of milk on a pale speckled surface
verdict

Calcium supplements: uses, evidence, dosing and safety

Aug 6, 2026

A macro close-up of human skin texture with fine hairs
verdict

Collagen: uses, evidence, dosing and safety

Aug 6, 2026

A pregnant woman in a coat resting both hands on her bump
verdict

Inositol: uses, evidence, dosing and safety

Aug 6, 2026

Cuts of raw red beef on a butcher counter
verdict

Iron supplements: uses, evidence, dosing and safety

Aug 6, 2026

Almonds and walnut halves scattered across a pale surface
verdict

Magnesium: uses, evidence, dosing and safety

Aug 6, 2026

Two salted salmon fillets on dark slate with lemon wedges and rosemary
verdict

Omega-3 and fish oil: uses, evidence, dosing and safety

Aug 6, 2026

A bowl of plain yogurt with strawberries and blueberries on a wooden table
verdict

Probiotics: uses, evidence, dosing and safety

Aug 6, 2026

Halved oranges and a grapefruit packed together, cut sides up
verdict

Vitamin C: uses, evidence, dosing and safety

Aug 6, 2026

A cannula taped into a patient forearm during an infusion, in black and white
News

High-dose vitamin D did not slow advanced bowel cancer

Aug 6, 2026

Sunlight dappled through a straw hat across a face
verdict

Vitamin D: uses, evidence, dosing and safety

Aug 6, 2026

Bunches of kale and dark leafy greens on a market stall
News

Vitamin K status did not protect bone in a VITAL analysis

Aug 6, 2026

Golden softgel capsules scattered across a white surface
verdict

Coenzyme Q10: uses, evidence, dosing and safety

Aug 5, 2026

Grey capsules spilled from a clear bottle onto a yellow background
verdict

NAC: uses, evidence, dosing and safety

Aug 5, 2026

Two cupped hands holding dark soil above a field
verdict

Selenium: uses, evidence, dosing and safety

Aug 5, 2026

A heap of pale dried ashwagandha roots on a patterned market cloth
verdict

Ashwagandha: uses, evidence, dosing and safety

Aug 3, 2026

Red barberry berries hanging from a thorned branch against soft green foliage
verdict

Berberine: uses, evidence, dosing and safety

Aug 3, 2026

Ground turmeric filling an open sack, with fragments of dried root through it
verdict

Turmeric and curcumin: uses, evidence, dosing and safety

Aug 3, 2026

Sliced raw beef resting on a wooden board in a dark kitchen
verdict

Vitamin B12: uses, evidence, dosing and safety

Aug 3, 2026

Fresh oysters on the half shell arranged on a platter of crushed ice
verdict

Zinc: uses, evidence, dosing and safety

Aug 3, 2026

A close-up of an older person's brown eye
News

A vitamin B3 supplement tracked far less glaucoma in at-risk eyes

Aug 2, 2026

A sleeping newborn wrapped in a white hospital blanket
News

Newborns who skipped vitamin K had triple the brain bleeds

Jul 28, 2026

A patient lying on the table of a CT scanner
News

Vitamin K2 slowed artery calcium in a two-year trial

Jul 26, 2026

A child holding a nebulizer mask to their face
News

Vitamin A, not D, tracked with better lungs in asthma

Jul 26, 2026

Softgel and capsule supplements scattered across a marble surface beside small bowls
News

US supplement use hit 60% as multivitamins fell and ashwagandha rose, across 25 years of data

Jul 25, 2026

A spoonful of white powder lifted from a glass storage jar on a wooden bench
verdict

Creatine: uses, evidence, dosing and safety

Jul 22, 2026

Golden fish oil capsules scattered on a pale blue background
News

Fish oil reached the brain but didn't protect it

Jul 22, 2026

A white bowl of fresh eggs on a wooden table
verdict

Phosphatidylcholine: uses, evidence, dosing and safety

Jul 22, 2026

Yellow softgel supplement capsules spilling from a white bottle
News

Calcium and vitamin D did little for fractures or falls

Jul 17, 2026

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