Performance & longevity compounds

A macro close-up of human skin texture with fine hairs

Collagen: uses, evidence, dosing and safety

Collagen is sold for skin and works better for joints. A 2025 review found that industry-funded studies showed a skin benefit and independently funded ones did not.

Aug 6, 2026

Two salted salmon fillets on dark slate with lemon wedges and rosemary

verdict

Omega-3 and fish oil: uses, evidence, dosing and safety

Omega-3 has the strongest single result of any supplement on this site, a high-certainty 15% cut in triglycerides. It also has a dose-dependent harm signal that almost nobody selling it mentions.

Aug 6, 2026

A spoonful of white powder lifted from a glass storage jar on a wooden bench

verdict

Creatine: uses, evidence, dosing and safety

Creatine builds strength and lean muscle alongside resistance training, and the evidence is unusually strong and consistent. The kidney and hair-loss fears are not supported. Memory effects are promising but unsettled.

Jul 22, 2026

Golden fish oil capsules scattered on a pale blue background

News

Fish oil reached the brain but didn't protect it

Researchers gave 365 older adults at higher risk of dementia high-dose fish oil or a placebo for two years. The omega-3 reached their brains, but memory, thinking and brain shrinkage were no different from placebo.

Jul 22, 2026