Explainer · Longevity & Aging
Tongue and interdental cleaning went with lower death rates in 9,676 older Japanese adults
Seven ordinary mouth-care habits were tested against six years of death records. Brushing twice a day and seeing a dentist did not separate the groups. Two less fashionable habits did.
- An observational study of 9,676 independent older adults in Japan, followed about six years.
- Seven routine mouth-care habits were compared against death from any cause.
- Using an interdental cleaner and using a tongue cleaner each went with a lower death rate.
- Brushing twice a day, mouthwash, toothpaste and dental visits showed no separate signal.
- People who clean between their teeth differ in many other ways, and that cannot be fully removed.
Dental advice is delivered with a confidence its evidence does not always earn. Floss daily, brush twice, see a dentist twice a year: the list is familiar enough that nobody asks which parts of it carry weight and which are habit dressed as science.
A Japanese study in the Journal of Dentistry put seven of those habits side by side and followed 9,676 older adults for six years to see who died. Two of the seven separated the groups, and neither was the one everybody repeats.
Why the mouth might matter for death from any cause
The link people usually reach for is the heart: gum disease causes chronic inflammation, inflammation damages arteries. That story is real but modest, and it is not the one the authors emphasize.
Their mechanism is the lungs. Older adults inhale small amounts of mouth material routinely, especially when swallowing weakens, and what gets inhaled carries whatever is growing in the mouth. The authors point at that pathway directly, calling for further investigation into potential mechanisms, including pathways related to aspiration and respiratory infections. Pneumonia acquired that way is a major cause of death in this age group and rarely gets discussed as a dental problem.
How seven mouth-care habits were compared
The data come from the Japan Gerontological Evaluation Study, a large national cohort, with participants enrolled in late 2016 and followed for death from any cause into 2023. Only functionally independent people with their own teeth were included, which removes the obvious confusion of counting people who were already failing.
Participants were categorized according to engagement in seven routine practices: brushing at least twice a day, interdental cleaner, tongue cleaner, toothpaste, mouthwash, and dental visits for treatment or for checkups. Each habit was then tested against mortality with models weighted to balance the groups on income, education, smoking, drinking, weight, walking time, living situation, self-rated health, number of teeth and depression.
During the 6-year follow-up, the mortality incidence rate was 17.3 per 1000 person-years among 9676 participants, whose average age was about 74.
Which oral health habits separated the groups
Two, and they are the ones people skip. Risk reductions in all-cause mortality were observed for interdental cleaner use and tongue cleaner use: about a tenth lower for cleaning between the teeth, and a little under a quarter lower for cleaning the tongue.
The other five did nothing detectable. Brushing twice a day, toothpaste, mouthwash and dental visits, whether for treatment or a checkup, showed no separate association with survival.
That pattern is less strange than it looks. Almost everyone in this cohort brushed and used toothpaste, and a habit that is nearly universal offers a study nothing to compare. Tongue cleaning is the opposite: common enough in Japan to measure, uncommon enough to divide the group.
Why the tongue result is the interesting one
Cleaning between the teeth has an established rationale and a plausible pathway through gum disease. The tongue does not. It is the more surprising finding and, at a roughly quarter-lower death rate, the larger one.
If the aspiration story is right, it makes sense: the tongue surface carries a dense bacterial population, and material from it is what reaches the lungs. On that reading a tongue scraper is not a cosmetic tool for breath but an infection-control measure for people whose swallowing is no longer reliable.
The study cannot demonstrate any of that. It measured habits and deaths, not pneumonia and not bacteria.
What a six-year cohort of 9,676 adults cannot show
The central problem is the one that haunts every study of a good habit: people who clean between their teeth are different from people who do not, in ways that stretch well beyond their mouths. They are more conscientious, more likely to attend to symptoms, more likely to take medicines as prescribed.
The analysis worked hard on that, weighting for a long list of factors and finding no significant effect modification across any of them. That is reassuring about the factors they measured. Conscientiousness is not one you can measure with a questionnaire.
The cohort is also Japanese, older and independent at enrollment, and six years is short for a mortality study in people averaging 74. Habits were self-reported once.
What to take from the interdental and tongue findings
The practical upshot is unusually cheap. Cleaning between your teeth has decent support from several directions, and this adds a small piece to it. A tongue cleaner costs almost nothing and carries no plausible harm, which is a rare combination in health advice, even if the evidence here cannot show cause.
The more useful message is about someone else. If you help care for an older relative, particularly one who is frail or has trouble swallowing, mouth care is not a cosmetic detail; it is plausibly about their lungs. MedlinePlus puts the basics simply: it’s important to take care of your mouth and teeth starting in childhood, because if you don’t, you could have problems with your teeth and gums. What this study adds is that the parts of that hygiene most often skipped may be the parts doing the most work.
People also ask
What did the study find?
During the 6-year follow-up the mortality incidence rate was 17.3 per 1000 person-years among 9,676 participants. Significant risk reductions in all-cause mortality were observed for interdental cleaner use (HR 0.89; 95% CI 0.80-0.99) and tongue cleaner use (HR 0.77; 95% CI 0.68-0.87). No effect modification was detected by age, sex, education, income, smoking, alcohol, body mass index, walking time, living status, self-rated health, number of teeth or depression.
What counts as an interdental cleaner?
Floss or an interdental brush: anything that cleans the surfaces between teeth, where a toothbrush does not reach. Roughly a third of each tooth's surface sits in that gap.
Why would a tongue cleaner matter?
The authors point at the lungs rather than the gums. The tongue carries a large bacterial population, and material from the mouth is routinely inhaled in small amounts, particularly in older adults. Pneumonia from that route is a major cause of death in this age group.
Why did brushing twice a day show nothing?
Probably because almost everybody does it, which leaves too little variation to detect a difference. A habit has to be uncommon before a study can compare those who do it with those who do not.
Could this just be healthier people flossing?
Partly, almost certainly. The analysis adjusted for income, education, smoking, drinking, weight, walking time and self-rated health, but people who clean between their teeth are conscientious in ways no questionnaire captures.
What should someone actually do?
Clean between your teeth, and if you or someone you care for is frail, keep the mouth clean generally. This is general information rather than medical advice.