News Sugar substitutes are linked to worse blood-sugar control
Researchers at Tufts University reviewed the evidence and ran a new meta-analysis of 21 randomized trials, published in Current Atherosclerosis Reports. Even against water or a placebo, non-nutritive sweeteners were tied to higher fasting insulin and a worse long-term blood-sugar marker, with the gut microbiome the likely route. These are metabolic markers, not proof of disease.
Jul 23, 2026